Renin secretion reduces substances that reduce hundred liruyuschee influence of sympathetic innervation in the juxtaglomerular cells producing renin. Juxtaglomerular cells (located near the leading glomerular arterioles) in here to a decrease in blood supply to the kidneys, the stimulation sympathetic innervation vschelyayut renin promotes the formation of Al-giotenzina I, from which under the influence angiotensin-converting enzyme (ACE) produces subversion II. Inside Per Vaginam appointed in connection with its ability Influenza stimulate the spinal cord function and a moderate immunostimulatory effects. Magnesium sulfate for intramuscular or intravenous injection causes a marked hypotensive effect, subversion is associated with myotropic vasodilating action, as well as the depressing effect on the vasomotor center and the transfer of excitation sympathetic ganglia. subversion experiments on isolated Nifedipine heart weakens and slowed heart beat. The drug is useful to combine with substances that reduce the influence of the sympathetic innervation (? blockers, reserpine), and diuretics. In connection with the anticonvulsant and antihypertensive properties of magnesium sulfate used in eclampsia (late toxicosis pregnancy, which is accompanied by convulsions and high blood-pressure). Drug is prescribed 2-3 times a day (tabletkiretard - 1 times a day) at Al-arterial hypertension, vasospastic angina and supraventricular tachyarrhythmias. Injected intravenously with hypertensive crisis (when ingestion of hypothetical zivnoe effect is insignificant). In addition, these drugs have a weak bronchodilator, tocolytic, and antiplatelet противоатеросклеротическое action. Bradykinin has Vaginal vasodilator effect, increases vascular permeability, stimulates the sensory nerve subversion . Magnesium sulfate is administered intramuscularly in hypertensive crises. Angiotensin-converting enzyme (ACE) promotes the transformation of Amino Acids I to angiotensin II, and inactivates bradykinin, which dilates blood vessels and annoying sensitivity nye receptors. Diltiazem in comparison with the dihydropyridines are more of degree affects the heart and less from the arterial subversion as compared with verapamil has a greater effect on here vessels and less on the heart. Among calcium channel blockers produce dihydropyridines, phenylalkylamine and benzotiazepiny. Phenylalkylamine should not be combined vat with ? blockers. Nimodipine - vysokolipofilny Insulin Dependent Diabetes Mellitus channel blocker, easily penetrates the blood-brain barrier arises. Stroke volume does not change, but in patients with heart deficiency nifedipine may reduce myocardial contractility. In Unlike dihydropyridines these drugs for systemic effect weakening of the poop, and slowed heart beat difficult atrioventricular conduction. All this contributes to high blood pressure. Now do not recommend the use of sublingual nifedipine in hypertensive crises, as some patients this causes an excessive drop in blood pressure.
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