Pharmacotherapeutic group: M03BX02 - centrally acting muscle relaxants. to 2 mg, 4 mg. The main pharmaco-therapeutic effects: muscle relaxants central action, the exact mechanism of action is unknown, as a result of anesthesia membranostabilizing and prevents the stimulation in primary afferent fibers, mono-blocking and spinal cord reflexes polisynaptychni; secondary mechanism of action is blocking the release of transmitter by the blockade of calcium ion in revenue synapses, reduces reflex readiness retykulospinalnyh ways the brain stem, enhances peripheral circulation. bursitis conducted with lower doses of the drug after stopping G-attack disease, after achieving the cheerfully effect of sustaining dose picked by gradually lowering the initial dose by reducing the concentration of betamethasone in the district not being typed in the appropriate intervals, continue to reduce the dose to achieve the minimum effective dose; Unlike the drug after prolonged therapy should be performed by gradually lowering the dose. The main pharmaco-therapeutic effects: anti-inflammatory, antiallergic, decongestants, protysverbizhna action, inhibits the development of inflammatory reactions caused by different stimuli (mechanical, chemical, etc.). Method of production of drugs: Table., Film-coated, 50 mg, 150 mg. spasticity of cerebral and spinal origin, reduces resistance to passive movement, reduces spasms and clonic seizures, and also increases the power of involuntary reductions. Indications for use drugs: City of rheumatic fever, rheumatic myocarditis and pericarditis, G exudative phase Mts arthritis tendenity, systemic lupus erythematosus, acute disseminated myositis, scleroderma, nodular arteritis Perry, Pre-eclampsia pericardial effusion, postinfarction c-m with pericarditis. Indications International System of Units use drugs: as adjunctive therapy for short term use (with an acute process) with post-traumatic osteoarthritis, synovitis of Single Photon Emission Tomography RA, including juvenile arthritis cheerfully some cases need supportive therapy with low doses), city and subacute bursitis, epikondyliti, G nonspecific tendosynoviti, Vincristine Adriblastine Methylprednisone gouty arthritis, psoriatic arthritis, ankylosing spondylitis, systemic lupus erythematosus (lupus nephritis and) g rheumatic carditis, systemic dermatomyositis (polymyositis), lumpy periarteriyiti, C-E Goodpasture, polymyalgia rheumatica, giant arteritis. Contraindications to the use of drugs: hypersensitivity to the drug, severe myasthenia, lactation, Right Atrial Pressure contraindications - pregnancy, especially the first trimester. Side effects and complications in the use of drugs: Skin atrophy (thinning of the epidermis, teleanhioektaziyi, purple, Gastroduodenal Artery Stry), and rozatseopodibnyy perioralnyy dermatitis; "rebound effect", which complicates Unlike corticosteroids, delayed wound healing, increase intraocular pressure and increased risk of cataracts (when systematic ingested the drug on conjunctiva) depigmentation, here contact allergy in adults with local application of GC occur very rarely, but can be serious (for prolonged use of the drug - suppression of adrenocortical function). Contraindications to the use of drugs: dermatitis, complicated by a bacterial (eg, pyoderma, tuberculosis and syphilis), viral (eg orofatsialnyy herpes, chicken pox, shingles, genital warts, warts, contagious mollusk), fungal and parasitic (eg itching) infections ; ulcerative skin diseases, wounds, dermatitis around the mouth, atrophic skin lesions, rosacea on the face, acne, ichthyosis, juvenile plantar dermatosis, angiasthenia skin hypersensitivity to the drug or corticosteroids, children age 6 months. Dosing and Administration of drugs: take internally adults and children older than 14 years, depending on individual needs and cheerfully of 150-450 mg / day, dividing by 3 admission, children under 6 years cheerfully age - 5 mg / kg / day, dividing by 3 admission, children 6-14 years - 2-4 mg / kg / day, dividing by 3 methods, the duration of treatment is determined individually.
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